Olusegun Emmanuel Thomas
University of Ibadan
Institution: University of Ibadan
Area of Research: Design, synthesis and genotoxicity evaluation of non-toxic azo dyes based on tetracyclic structures
I obtained a PhD from the University of Ibadan in 2017. The broad area of research for my doctoral studies was in synthetic chemistry and chemical biology with focus on the synthesis and genotoxicity evaluation of azo-based compounds that can be used in modelling the hazard potential of existing colourants in the food and textile industries. A major output of my doctoral study is the ongoing application for a Nigerian patent of ten novel mono azo compounds which are being registered as alternatives for standard food colourants. In addition, a number of manuscripts arising from the thesis have been prepared and are ready for publication pending the completion of the patent filing. In the long term, my research interests include chemical toxicology, genotoxicity and biological profiling. I’m particularly interested in the study of human populations exposed to potential chemical carcinogens and environmental pollutants. I have published papers on the toxicity of food additives, heavy metal poisoning of paediatric formulations and currently have undergoing peer-review a paper on the use of micronuclei frequency as a biomarker of cancer among textile dye applicators in Abeokuta, Nigeria. I am at present a Senior Lecturer/Researcher at the University of Ibadan and I’m always seeking to acquire new collaborations, research skills and hands-on experience that can further strengthen my academic/research pursuit especially in the areas of bioassays and biological activity profiling of low-molecular chemical compounds. I was a visiting scholar at the Centre for Advanced Cell and Chromosome Research, University of Calcutta, Kolkata India in 2016, the Radiobiology Laboratory, Department of Radiation Sciences, University of Witwatersrand, South Africa in 2019. I’m scheduled under the 2020/21 COIMBRA programme for a two-month hands-on experience in the design of assays that can detect and quantify epigenomic changes induced by behavior and environment of exposed persons.